Bio Age, Test & Diagnostics 524

PSA Ratio

2 min read

Simon Körösi

Reviewed by: Dr. Tareq Alsaody

What is PSA ratio?


PSA ratio is the relative relationship between free, unbound PSA and the total PSA (bound and unbound). To learn your PSA ratio, you need to measure your free PSA and your total PSA. To calculate the PSA ratio, you then divide the value of free PSA by the total level of PSA.



Why measure PSA ratio?


A normal to high PSA ratio might indicate a lower risk of invasive prostate cancer. 


Measuring the ratio of free PSA to total PSA provides information when screening for and managing prostate cancer.



What does a high PSA ratio mean?


A high PSA ratio (greater than 18%), indicates a lower risk of prostate cancer. The reason behind this, is that non-cancerous conditions such as enlargement of the prostate gland (BPH) tend to show a higher ratio than prostate cancer. 


Important note: A high PSA ratio cannot alone rule out the possibility of prostate cancer. Further testing and investigation may be necessary depending on factors such as symptoms, age and other diagnostic tools.



What does a low PSA ratio mean?


A low PSA ratio (below 18%) may indicate an increased risk of prostate cancer. If a PSA ratio is low, further diagnostic tests may be recommended to confirm or deny the presence of prostate cancer. If PSA ratio is decreasing after a cancer treatment, it can indicate that the treatment is effective.


Important note: A low PSA ratio alone is not enough to diagnose prostate cancer. If a PSA ratio is low, further tests and investigations are needed to understand the underlying cause.



Take the Sn™900 CheckUp™test